Title: Head of Supply Platform (CMC, Quality& Supply Chain)
Level: AVP
Location: Singapore
Reporting to: CEO
About the Role
Moleac is a biopharmaceutical company focused on addressing unmet medical needs by bringing innovative products to patients in more than 35 countries. With a dynamic, fast-paced, and mission-driven environment, Moleac is committed to improving health outcomes and delivering quality through excellence in our global operations.
Moleac owns the intellectual property and manufacturing know-how of its product. The strategy is to operate an effective, cost-efficient supply chain while ensuring high standard of quality and consistency among the network of CMOs managed in China and Singapore.
The Head of Supply Platform is a senior, AVP role responsible for overseeing and executing the company’s end-to-end supply, technical, and quality strategy, while proactively derisking the supply platform weak points by ensuring operational flexibility and supply redundancy. This position will be responsible for the integrated management a team of 8 in Chemistry, Manufacturing & Controls (CMC), Quality, and Supply Chain departments, ensuring these functions operate as a unified, agile platform that enables sustainable growth and global product delivery.
The role is accountable for building a resilient, scalable, and compliant supply ecosystem, aligning technical development with commercial objectives, and ensuring the reliable delivery of high-quality pharmaceutical products across all markets. Success in this role depends on the ability to translate strategy into execution, diagnose root causes, and drive outcomes through direct involvement where needed.
Key Responsibilities
1. Enterprise Supply Strategy & Platform Leadership
· Drive and implement the integrated strategy across CMC, Quality, and Supply Chain as a unified business platform, ensuring the robustness and health of its multi-supplier network of CMO, suppliers and laboratories.
· Align supply, technical, and quality strategies and operational KPIs with corporate objectives, portfolio priorities, and growth plans
· Continue to build a scalable operating model that supports both current and future product and pipeline growth
· Serve as a key member of the leadership team, contributing to management-level decision-making
· Integrate technical (CMC) expertise into supply chain and cost strategies, ensuring cost of goods optimization through informed process, formulation, and manufacturing decisions
· Act as the ultimate escalation point for critical supply, quality, or technical issues, personally leading root cause analysis and resolution efforts when required
· Balance high-level strategic oversight with situational hands-on involvement to unblock execution challenges across functions
2. ExternalPartner Strategy & Commercial Oversight
- Define and execute the company’s externalization strategy, including selection and governance of CMOs, laboratories, and key suppliers
- Together or under the guidance of Head of Pharma Partnerships, to build and maintain strategic partnerships that support quality, cost efficiency, and long-term reliability
- Maintain and update contracts, engage in commercial negotiations and ensure alignment between contractual frameworks and business objectives
3. CMC &Technical Stewardship (working with R&D/Patent/Regulatory)
- Set the strategic direction for CMC development, taking into consideration the quality, cost and regulatory requirements.
- Oversee lifecycle planning, contribute to patent strategy and ensuring robustness and continuity of supply
- Ensure effective integration of process development, technology transfer, and manufacturing readiness into long-term supply strategy
4. Product Quality Leadership
- Establish and sustain product quality vision for supply and production grounded in proactive, risk-based decision-making, aligning with corporate QA/compliance.
- Ensure the effectiveness of related quality systems and ongoing regulatory compliance (GMP, GDP)
- Drive a culture of quality that balances compliance with operational agility and business needs
5. Supply Chain& Commercial Delivery oversight
- Oversee and continuously optimize a resilient global supply network, including manufacturing, logistics, and supplier ecosystems
- Design and lead a resilient supply ecosystem capable of anticipating disruption, rapidly adapting to change, and ensuring uninterrupted delivery of critical products
- Integrate supply chain planning with commercial demand and portfolio evolution
- Anticipate and ensure commercial markets with quality products delivered on time and on target
- Own crisis response and de-escalation end-to-end, including personally leading deep-dive investigations into technical, operational, or supplier issues, and ensuring CAPAs are effectively implemented and sustained
- Establish clear escalation frameworks and personally intervene in high-risk or high-impact situations to ensure execution discipline and timely outcomes
6.Cross-Functional Integration
- Drive alignment across R&D, Regulatory, and Commercial teams to ensure seamless transition from development to market
- Enable informed trade-offs between quality, cost, timelines, and risk at the enterprise level
- Foster collaboration and transparency across functions to support integrated decision-making
7. Organizational Leadership & Capability Building
- Lead, develop, and inspire a multidisciplinary team across CMC, Quality, and Supply Chain
- Build organizational capabilities aligned with the company’s growth strategy, ensuring the right structure, skills, and succession plans are in place
- Foster a high-performance culture grounded in accountability, collaboration, and continuous improvement
- Drive talent development, coaching, and performance management across the function
- Ensure effective resource planning and prioritization to support evolving business needs
Qualifications & Experience
- Degree in Chemistry, Pharmaceutical Sciences, Chemical Engineering, or related field (advanced degree preferred)
- 15+ years in pharmaceutical/biotech industry
- Demonstrated experience in strategic supply planning, CMC, and/or quality leadership
- Proven track record in risk management and supply network design
- Strong knowledge of GxP and regulatory expectations
- Proven leadership experience in cross-functional or integrated roles
- Strong command of Mandarin and English language to liaise with CMO partners in Singapore and China
Key Competencies
- Ability to operate at both strategic and operational levels, with strong attention to detail when required
- Demonstrated willingness to personally engage in complex problem-solving and execution under pressure
- Strong risk assessment and scenario planning capability
- Excellent decision-making and problem-solving skills
- Sound judgment in balancing quality, cost, and timelines
- Influential leadership across functions
- Commercial and financial acumen
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